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What to Expect During Your First Wegovy Injection Week

  • Writer: aliza khan
    aliza khan
  • Jun 26
  • 4 min read

For anyone beginning their weight loss journey with medical support, starting a treatment like Wegovy can feel both exciting and nerve-wracking. Questions naturally arise: How will your body react? Will you feel different right away? What should you be doing to make the most of it? These are all valid concerns, especially for patients beginning their first dose at a trusted Wegovy Injections Clinic in Muscat.

This detailed guide offers a friendly yet informative look at what you can expect during your first week on Wegovy—from physical symptoms to emotional shifts, helpful tips, and expert guidance to set you on the path to success.



What Is Wegovy and Why It's Used:

Wegovy is the brand name for semaglutide, a once-weekly injectable medication used for chronic weight management. It’s FDA-approved for adults with:

  • A BMI of 30 or more (obesity)

  • A BMI of 27 or more with at least one weight-related condition (like high blood pressure or type 2 diabetes)

Semaglutide is part of a class of medications known as GLP-1 receptor agonists, which mimic the natural hormone GLP-1 to regulate appetite, digestion, and insulin.

Clinics that offer Wegovy injections in Muscat typically provide a full assessment and create a personalized plan, making the transition into your first week smoother and more supported.

Wegovy Injections Clinic in Muscat
Wegovy Injections Clinic in Muscat

What Happens in the First Week of Wegovy?

Your first week will generally start with the lowest dose: 0.25 mg, allowing your body to adjust gradually and minimizing side effects. Here’s what you might experience:


Appetite Changes:

One of the earliest signs that Wegovy is starting to work is a noticeable reduction in hunger. Many people find they feel fuller after meals or aren’t as interested in snacking.

However, not everyone experiences this right away. Some patients may need a few weeks of dose escalation before noticing significant appetite suppression.

Pro Tip:Try to eat mindfully even if your appetite hasn't changed dramatically. This helps your body adjust and sets good habits from the start.


Mental and Emotional Shifts:

Your first week on Wegovy isn’t just physical—it can also trigger emotional changes. Some people feel optimistic, hopeful, and more in control of their eating. Others might feel a bit anxious about how their body is responding.

This is normal. The key is to keep a supportive mindset, track how you're feeling, and stay in touch with your clinic team for reassurance or advice.


What to Eat During Week One:

Eating well supports Wegovy’s effects and minimizes side effects. In your first week, aim for:

  • Small, balanced meals

  • High-protein snacks (like yogurt, nuts, or boiled eggs)

  • Low-fat, low-sugar foods

  • Plenty of water (at least 8 glasses per day)

Avoid large, heavy meals that can worsen nausea. Most clinics, including those offering Wegovy injections in Muscat, provide dietary counseling as part of your program.


Activity and Movement:

Light physical activity can ease digestion and improve energy levels, especially during the adjustment phase. You don’t need to start an intense workout routine in Week 1. Instead:

  • Go for short walks after meals

  • Try light stretching or yoga

  • Aim for gentle movement daily

Your clinic may help you develop a fitness plan tailored to your current health and mobility level.

Wegovy Injections Clinic in Muscat
Wegovy Injections Clinic in Muscat

Support from Your Wegovy Injections Clinic in Muscat:

One of the biggest advantages of starting Wegovy in a professional clinic setting is the built-in support system. Your clinic should offer:

  • Regular check-ins and follow-ups

  • Access to dietitians or nutritionists

  • Side effect management strategies

  • Ongoing education and motivation

Choosing the right clinic means you’re never alone on your journey. Top clinics in Muscat provide holistic care that goes beyond the injection itself.



Setting Realistic Expectations:

While it’s tempting to look for fast results, remember that Wegovy is a long-term solution, not a quick fix. Most patients start seeing measurable weight loss after 4 to 8 weeks, depending on dosage progression and lifestyle habits.

Use your first week as a time to:

  • Observe your body's reactions

  • Create new eating patterns

  • Commit to small, sustainable changes

Think of this week as the foundation of a healthier future, not the finish line.



FAQs:

1. Will I lose weight in the first week?

Some people may drop a small amount of weight due to appetite reduction or water loss, but significant fat loss usually takes a few weeks. Be patient—Wegovy works over time.


2. Is nausea normal during Week 1?

Yes, mild nausea is one of the most common side effects and is usually temporary. Eating smaller meals and avoiding rich foods can help.


3. Can I exercise during my first week?

Yes, but keep it light. Walking, stretching, and low-impact activities are best while your body adjusts.


4. Do I need to change my diet right away?

It helps to begin making healthier choices, but a total overhaul isn’t necessary on Day 1. Gradual changes are more sustainable.


5. What happens if I forget my first dose?

If it’s within 5 days, you can still take the missed dose. If more time has passed, skip it and continue with your next scheduled injection. Always follow your clinic's instructions.


6. Will I feel different immediately after the injection?

No, the effects aren’t instantaneous. The medication gradually builds up in your system, so any changes typically develop over several days.



Final Thoughts:

Your first week on Wegovy is the beginning of a transformative journey. While there may be some discomfort or uncertainty, the benefits of this FDA-approved medication are well-supported by science and patient success stories. From appetite control to more sustainable eating habits, Wegovy helps the body and mind work together toward better health.

 
 
 

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